133661-18-4

Basic information

• Product Name: (1R,2S,4R,6S)-4-Benzyloxy-8,8-dichloro-1,2-dimethyl-bicyclo[4.2.0]octan-7-one
• Synonyms: (1R,2S,4R,6S)-4-Benzyloxy-8,8-dichloro-1,2-dimethyl-bicyclo[4.2.0]octan-7-one
• CAS NO: 133661-18-4
• Molecular Weight: 327.251
• Mol File: 133661-18-4.mol

Chemical Properties

• CAS DataBase Reference: (1R,2S,4R,6S)-4-Benzyloxy-8,8-dichloro-1,2-dimethyl-bicyclo[4.2.0]octan-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,4R,6S)-4-Benzyloxy-8,8-dichloro-1,2-dimethyl-bicyclo[4.2.0]octan-7-one(133661-18-4)
• EPA Substance Registry System: (1R,2S,4R,6S)-4-Benzyloxy-8,8-dichloro-1,2-dimethyl-bicyclo[4.2.0]octan-7-one(133661-18-4)

Safety Data

• Hazardous Substances Data: 133661-18-4(Hazardous Substances Data)

Upstream product

• 133661-16-2 (1SR,5SR)-4,5-dimethylcyclohex-3-en-1-ol 
• 133661-15-1 4,5-dimethyl-3-cyclohexen-1-one 
• 133661-17-3 (1SR,5SR)-1-benzyloxy-4,5-dimethylcyclohex-3-ene 
• 76-02-8 trifluoroacetyl chloride 

Downstream Products

• 133661-24-2 (1RS,3SR,4RS,5SR)-3,4-diiodomethyl-4,5-dimethylcyclohexan-1-ol 
• 133661-25-3 (1RS,3SR,4RS,5SR)-3,4-diiodomethyl-4,5-dimethylcyclohexan-1-one 
• 133661-21-9 ((1R,2S,4R,6S)-4-Benzyloxy-2-hydroxymethyl-1,6-dimethyl-cyclohexyl)-methanol 
• 133661-22-0 (1RS,3SR,4RS,5SR)-[4-benzyloxy-1,6-dimethyl-2-iodomethyl]cyclohexyliodomethane 
• 133661-23-1 Trifluoro-methanesulfonic acid (1R,2S,4R,6S)-4-benzyloxy-1,2-dimethyl-6-trifluoromethanesulfonyloxymethyl-cyclohexylmethyl ester 
• 133661-20-8 (1RS,2SR,4RS,6SR)-dimethyl-4-benzyloxy-1,6-dimethylcyclohexane-1,2-dicarboxylate 

Relevant articles and documents

Stereoselective synthesis of homogynolide-A, A bakkane from homogyne alpina

Homogynolide-A, an antifeedant sesquiterpene, has been stereoselectively prepared from benzoquinone.

First comprehensive bakkane approach: Stereoselective and efficient dichloroketene-based total syntheses of (±)- and (-)-9-acetoxyfukinanolide, (±)- and (+)-bakkenolide a, (-)-bakkenolides III, B, C, H, L, V, and X, (±)- and (-)-homogynolide A, (±)-homogynolide B, and (±)-palmosalide C

Cycloaddition of dichloroketene with dimethylcyclohexenes has been used as the key reaction in an efficient, general approach to the bakkanes. New methods and methodologies that have been developed in this work include spiro β-methylene-γ-butyrolactonizations, a vicinal dicarboxylation, an angelic ester preparation, a transesterification, an epoxy ketone double reduction, and a retro aldol-aldol approach to low-energy aldol isomers.