13369-82-9Relevant academic research and scientific papers
Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus
Bahnous, Mebarek,Bouraiou, Abdelmalek,Chelghoum, Meryem,Bouacida, Sofiane,Roisnel, Thierry,Smati, Farida,Bentchouala, Chafia,Gros, Philippe C.,Belfaitah, Ali
, p. 1274 - 1278 (2013/03/14)
Several new highly functionalized imidazolium derivatives were synthesized, via appropriate synthetic routes, using imidazole, 1-methylimidazole and 2-phenyl-1-methylimidazole as key intermediates. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella thipymurium using disk-diffusion and MIC methods. Crystal X-ray structures are reported for six compounds.
A Pd-catalyzed double coupling reaction to 4,5-disubstituted imidazole alkynes
Kim,Kang,Ryu,Keum,Seo
, p. 507 - 512 (2007/10/03)
A palladium-catalyzed double coupling reaction of 4,5-diiodoimidazoles 2, which were prepared by diiodination of imidazole, and terminal alkynes provided the corresponding imidazole diynes 3.
Electron Spin Resonance Studies of Electron Capture Processes. Part 7. ?* (3-Electron Covalent Bond) Radical Anions of Halogenoimidazoles
Symons, Martyn C. R.,Bowman, W. Russell
, p. 975 - 979 (2007/10/02)
Exposure of dilute solutions of 4-bromo- and 4-iodo-2-methylimidazole, 5-bromo- and 5-iodo-1,2-dimethylimidazole, and 4,5-dibromo- and 4,5-diiodo-1,2-dimethylimidazole in methanol (CD3OD) or methyltetrahydrofuran (MeTHF) to 60Co γ-rays at 77 K resulted in electron addition to yield not the expected ?* radical anions but ?* radical anions.In these radical anions the SOMO is primarly the C-Hal ?* molecular orbital with little delocalisation into the imidazole ring, i.e. a 3-electron ? bond.On slowly increasing the temperature of the MeTHF solutions of the bromoimidazoles the hyperfine features for the ?* radical anions were lost but with no clear concomitant growth of features assignable to 4- or 5-imidazolyl radicals.However, for the iodoimidazoles (2), (4), and (6) in CD3OD a new species was observed on annealing.The same species was observed for all three iodo compounds and is assigned to iodine atoms weakly bonded to CD3OD molecules O(D)CD3>.The results are discussed in the light of the ?* and/or ?* species obtained from electron capture by other aromatic halides and other substituted imidazoles.
