1336986-07-2 Usage
Description
1-(6-Chlorophenyl-2,3,4,5-d4)-7-oxabicyclo[4.1.0]heptane is a complex organic compound characterized by its unique molecular structure, which includes a chlorophenyl group and a deuterated bicyclic ring. 1-(6-Chlorophenyl-2,3,4,5-d4)-7-oxabicyclo[4.1.0]heptane is an isotope-labeled variant of 1-(6-chlorophenyl)-7-oxabicyclo[4.1.0]heptane, with deuterium atoms replacing hydrogen atoms in the molecule. Its deuterated nature makes it particularly useful in various analytical and research applications.
Uses
Used in Pharmaceutical Industry:
1-(6-Chlorophenyl-2,3,4,5-d4)-7-oxabicyclo[4.1.0]heptane is used as a labeled compound for the preparation of labeled ketamine metabolites. The incorporation of deuterium atoms in the molecule allows for enhanced detection and tracking of these metabolites in pharmacokinetic and pharmacodynamic studies, which can be crucial in understanding the metabolism, distribution, and excretion of ketamine in the body.
Used in Analytical Chemistry:
As an oil with deuterated properties, 1-(6-Chlorophenyl-2,3,4,5-d4)-7-oxabicyclo[4.1.0]heptane can be employed in various analytical techniques that require stable isotope labeling. These techniques may include mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and infrared (IR) spectroscopy, where the deuterium-labeled compound can serve as an internal standard or a reference compound for accurate quantification and identification of other molecules in a sample.
Used in Research and Development:
The compound can also be utilized in research and development settings, particularly in the fields of medicinal chemistry and drug discovery. Its unique structure and deuterated properties make it a valuable tool for studying molecular interactions, testing new synthetic methods, and developing novel drug candidates with potential applications in various therapeutic areas.
Check Digit Verification of cas no
The CAS Registry Mumber 1336986-07-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,6,9,8 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1336986-07:
(9*1)+(8*3)+(7*3)+(6*6)+(5*9)+(4*8)+(3*6)+(2*0)+(1*7)=192
192 % 10 = 2
So 1336986-07-2 is a valid CAS Registry Number.
1336986-07-2Relevant articles and documents
Synthesis of deuterium labeled ketamine metabolite dehydronorketamine- d4
Sulake, Rohidas S.,Chen, Chinpiao,Lin, Huei-Ru,Lua, Ahai-Chang
, p. 5719 - 5721 (2011/10/19)
A convenient synthesis of ketamine metabolite dehydronorketamine-d 4, starting from commercially available deuterium labeled bromochlorobenzene, was achieved. Key steps include Grignard reaction, regioselective hydroxybromination, Staudinger re
