133705-03-0

Basic information

• Product Name: 4'-(2-n-butyl-3H-imidazo<4,5-c>pyridin-3-ylmethyl)biphenyl-2-carbonitrile
• CAS NO: 133705-03-0
• Molecular Weight: 366.465
• Mol File: 133705-03-0.mol

Chemical Properties

• CAS DataBase Reference: 4'-(2-n-butyl-3H-imidazo<4,5-c>pyridin-3-ylmethyl)biphenyl-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-(2-n-butyl-3H-imidazo<4,5-c>pyridin-3-ylmethyl)biphenyl-2-carbonitrile(133705-03-0)
• EPA Substance Registry System: 4'-(2-n-butyl-3H-imidazo<4,5-c>pyridin-3-ylmethyl)biphenyl-2-carbonitrile(133705-03-0)

Safety Data

• Hazardous Substances Data: 133705-03-0(Hazardous Substances Data)

Upstream product

• 109-52-4 valeric acid 
• 54-96-6 3,4-diaminopyridine 
• 114772-54-2 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile 
• 133239-95-9 2-n-butyl-imidazo<4,5-c>pyridine 

Relevant articles and documents

Biphenylmethane derivative and pharmacological use

The biphenylmethane derivative having the formula (I) is useful to prevent and treat hypertension and cardiac failure. STR1 in which R1 is hydrogen, an alkyl, a cycloalkyl, a halogenated alkyl, --S--R7, --SO2--R7, --C C--R7 or --(CH2)--OR7, R7 being hydrogen, an alkyl, a cycloalkyl or a halogenated alkyl, p being zero or 1, --A1=A2--A3=A4-- is CH=CH--CH=CH--, --N=CH--CH=CH--, --CH=N--CH=CH--, --CH=CH--N=CH--, --CH=CH--CH=N-- or --CH=N--CH=N--, R2 and R3 are each hydrogen, a halogen, a lower alkyl, a lower alkoxy, a carbamoyl or cyano, R4 is hydrogen or a lower alkyl, R5 is 1H-tetrazol-5-yl, carboxyl (--COOH) or a carboxylic ester and R6 is hydrogen, a halogen, hydroxyl or a lower alkoxy, or a pharmacologically acceptable salt thereof.

Synthesis and Structural Assignment of Some N-Substituted Imidazopyridine Derivatives

A synthesis of all possible N-alkylated 2-n-butyl-imidazopyridine isomers is described as well as their structural assignment by (1)H NMR specroscopy.One of these derivatives, 2-n-butyl-3--3H-imidazopy