133705-03-0Relevant articles and documents
Biphenylmethane derivative and pharmacological use
-
, (2008/06/13)
The biphenylmethane derivative having the formula (I) is useful to prevent and treat hypertension and cardiac failure. STR1 in which R1 is hydrogen, an alkyl, a cycloalkyl, a halogenated alkyl, --S--R7, --SO2--R7, --C C--R7 or --(CH2)--OR7, R7 being hydrogen, an alkyl, a cycloalkyl or a halogenated alkyl, p being zero or 1, --A1=A2--A3=A4-- is CH=CH--CH=CH--, --N=CH--CH=CH--, --CH=N--CH=CH--, --CH=CH--N=CH--, --CH=CH--CH=N-- or --CH=N--CH=N--, R2 and R3 are each hydrogen, a halogen, a lower alkyl, a lower alkoxy, a carbamoyl or cyano, R4 is hydrogen or a lower alkyl, R5 is 1H-tetrazol-5-yl, carboxyl (--COOH) or a carboxylic ester and R6 is hydrogen, a halogen, hydroxyl or a lower alkoxy, or a pharmacologically acceptable salt thereof.
Synthesis and Structural Assignment of Some N-Substituted Imidazopyridine Derivatives
Mederski, Werner W. K. R.,Pachler, Klaus G. R.
, p. 10549 - 10558 (2007/10/02)
A synthesis of all possible N-alkylated 2-n-butyl-imidazopyridine isomers is described as well as their structural assignment by (1)H NMR specroscopy.One of these derivatives, 2-n-butyl-3--3H-imidazopy