133719-64-9

Basic information

• Product Name: diethyl 4-pyrimidin-5-yl)ethyl>amino>benzoyl-L-glutamate
• Synonyms: diethyl 4-pyrimidin-5-yl)ethyl>amino>benzoyl-L-glutamate
• CAS NO: 133719-64-9
• Molecular Weight: 497.554
• Mol File: 133719-64-9.mol

Chemical Properties

• CAS DataBase Reference: diethyl 4-pyrimidin-5-yl)ethyl>amino>benzoyl-L-glutamate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 4-pyrimidin-5-yl)ethyl>amino>benzoyl-L-glutamate(133719-64-9)
• EPA Substance Registry System: diethyl 4-pyrimidin-5-yl)ethyl>amino>benzoyl-L-glutamate(133719-64-9)

Safety Data

• Hazardous Substances Data: 133719-64-9(Hazardous Substances Data)

Upstream product

• 1118-89-4 diethyl-L-glutamate hydrochloride 
• 133719-61-6 ethyl 4-pyrimidin-5-yl)ethyl>amino>benzoate 
• 165900-67-4 ethyl 4-pyrimidin-5-yl)ethyl>-N-(tert-butoxycarbonyl)amino>benzoate 
• 165900-68-5 ethyl 4-pyrimidin-5-yl)ethyl>amino>benzoate 
• 134621-57-1 ethyl 4-(2,4-diamino-4b,5,6,7,7a,8-hexahydropyrrolo<3',2':4,5>pyrrolo<2,3-d>pyrimidin-7-yl)benzoate 

Relevant articles and documents

Synthesis and antitumor activity of pyrrolo[2,3-d]pyrimidine antifolates with a bridge chain containing a nitrogen atom

Novel pyrrolo[2,3-d]pyrimidine antifolates (1a, b and 2a, b) with a nitrogen atom in the bridge chain between the 2,4-diaminopyrrolo[2,3-d]pyrimidine and phenylene rings were designed and efficiently synthesized. These compounds exhibited more potent inhi

Pyrrolopyrimidines, their production and use as tumoricidal agents

A compound of the formula (I) wherein the ring A?may be hydrogenated, X is an amino, hydroxyl or mercapto group, Y is a hydrogen atom or a hydroxyl group, R1, R2, R4 and R5 are each a hydrogen atom, a lower hydrocarbon radical or a chemical bond, Z is -O-, a group of the formula -S(O)n- (n is 0 to 2), or a group of the formula in which R3 is a hydrogen atom, a lower hydrocarbon radical optionally having substituent(s), a group attached through -CO- or -S(O)m (m is 1 or 2) or a chemical bond, -B?- is a divalent cyclic group optionally having substituent(s) or a lower alkylene group optionally having substituent(s), -COOR6 and -COOR7 are each a carboxyl group optionally esterified, and i and j are an integer of 0 to 3 provided that i + j= 1 to 3, or its salt, which is useful as antitumor agent.