165900-67-4

Upstream product

• 50-01-1 guanidine hydrochloride 
• 109-77-3 malononitrile 

Downstream Products

• 133719-64-9 diethyl 4-pyrimidin-5-yl)ethyl>amino>benzoyl-L-glutamate 
• 133719-62-7 diethyl 4-pyrimidin-5-yl)ethyl>amino>benzoyl-L-glutamate 
• 134621-57-1 ethyl 4-(2,4-diamino-4b,5,6,7,7a,8-hexahydropyrrolo<3',2':4,5>pyrrolo<2,3-d>pyrimidin-7-yl)benzoate 
• 133719-61-6 ethyl 4-pyrimidin-5-yl)ethyl>amino>benzoate 
• 1027660-30-5 4-pyrimidin-5-yl)ethyl>amino>benzoic acid 
• 165900-68-5 ethyl 4-pyrimidin-5-yl)ethyl>amino>benzoate 

Relevant academic research and scientific papers

Synthesis and antitumor activity of pyrrolo[2,3-d]pyrimidine antifolates with a bridge chain containing a nitrogen atom

Novel pyrrolo[2,3-d]pyrimidine antifolates (1a, b and 2a, b) with a nitrogen atom in the bridge chain between the 2,4-diaminopyrrolo[2,3-d]pyrimidine and phenylene rings were designed and efficiently synthesized. These compounds exhibited more potent inhi