13375-88-7

Usage

Physical State

Colorless liquid

Solubility

Insoluble in water

Vapor Pressure

Very low

Primary Uses

a. Solvent in industrial applications
b. Production processes for chemicals and pharmaceuticals
c. Intermediate in the synthesis of other compounds
d. Pesticide

Health Hazards

a. Harmful if inhaled (respiratory system irritation)
b. Potentially harmful if ingested
c. Potentially harmful if skin contact occurs

Safety Measures

Handle with care and follow appropriate safety protocols when working with 1,1,1,3-Tetrachloroheptane.

InChI:InChI=1/C7H12Cl4/c1-2-3-4-6(8)5-7(9,10)11/h6H,2-5H2,1H3

Upstream product

• 56-23-5 tetrachloromethane 
• 592-41-6 1-hexene 
• 73927-91-0 tributylstannyl iodoacetate 

Downstream Products

• 56686-57-8 1,1,3-trichloroheptane 

Relevant academic research and scientific papers

Addition of CCl4 to olefins catalyzed by chromium and ruthenium complexes: The influence of water as a nucleophilic additive

The feasibility of the addition of CCl4 to linear and cyclic olefins and dienes in the presence of chromium and ruthenium complexes was established. The influence of water as a nucleophilic additive and the influence of the olefin nature, the c

Formation of three-membered rings by SHi displacement. Reverse of cyclopropyl ring opening

The general methods, photoinitiated or peroxide-initiated free radical chain additions of halomethanes to olefins, yield 1,2-addition products at temperatures ranging from 20 to 100°C. At lower temperatures, -42 to -104°C, a competitive reaction, subsequent to the addition of CCl2X., yields alkylcyclopropanes. The reactions of 1-octene or 1-hexene and 1-methylcyclohexene with atomic hydrogen carried out in the presence of several transfer agents (CCl4, CCl3Br, CCl2Br2) initiate a radical chain addition of CCl2X. and yield cyclized materials resulting from the SHi displacement of halogen by a carbon-centered radical. The radical displacement of a halogen on carbon, the reverse of homolytic displacement on cyclopropyl carbon, is dominant at low temperatures. The rate constants for cyclization (kc) vs transfer with halomethane (kt) showed isokinetic temperatures of -46°C (CCl4, 1-hexene); -35°C (CCl4, 1-methylcyclohexene). The isokinetic temperatures for the reactions of the two substrates carried out in the presence of BrCCl3 were calculated as -204 °C (1-octene) and -109°C (1-methylcyclohexene).

MECHANISM OF THE ADDITION OF TRIBUTYLTIN IODOACETATE TO ALKENES

The mechanism of the formation of lactones by free radical additions of tri-n-butyltin iodoacetate to alkenes occurs through a two-step process: a homolytic addition of the ester (addition of .CH2-CO2SnBu3, iodine transfer), followed by a fast ionic cyclization with elimination of tri-n-butyltin iodide.