1337531-86-8

Basic information

• Product Name: 5-{1-[(4-fluorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• Synonyms: 5-{1-[(4-fluorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• CAS NO: 1337531-86-8
• Molecular Weight: 401.443
• Mol File: 1337531-86-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-{1-[(4-fluorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-{1-[(4-fluorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine(1337531-86-8)
• EPA Substance Registry System: 5-{1-[(4-fluorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine(1337531-86-8)

Safety Data

• Hazardous Substances Data: 1337531-86-8(Hazardous Substances Data)

Upstream product

• 1266343-30-9 5-bromo-4-chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine 
• 837392-67-3 1,1-dimethylethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indole-1-carboxylate 
• 1391053-27-2 1,1-dimethylethyl 5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indole-1-carboxylate 
• 22190-33-6 5-bromoindoline 
• 1337532-51-0 5-bromo-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine 
• 1337533-85-3 5-(2,3-dihydro-1H-indol-5-yl)-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine dihydrochloride 
• 405-50-5 p-Fluorophenylacetic acid 

Relevant articles and documents

COMPOUNDS AND METHODS FOR TREATING INSULIN RESISTANCE SYNDROME

The present invention relates to a method of treating or preventing insulin resistance syndrome in an animal body by administering an inhibitor of protein kinase RNA-like endoplasmic reticulum kinase (PERK) gene, or a functional variant thereof, or an inhibitor of PERK protein or a functional variant thereof or a method of reducing activity of transcription factors of the FOXO family (Foxo 1, 3a, 4 and 6) by administering an inhibitor of protein kinase RNA-like endoplasmic reticulum kinase (PERK) gene, or a functional variant thereof, or an inhibitor of PERK protein or a functional variant thereof. The present invention also relates to different compounds and methods for using PERK gene or PERK protein.