1337567-05-1

Basic information

• Product Name: C₃₂H₂₃BrClF₃N₆
• Synonyms: C₃₂H₂₃BrClF₃N₆
• CAS NO: 1337567-05-1
• Molecular Weight: 663.927
• Mol File: 1337567-05-1.mol

Chemical Properties

• CAS DataBase Reference: C₃₂H₂₃BrClF₃N₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₂H₂₃BrClF₃N₆(1337567-05-1)
• EPA Substance Registry System: C₃₂H₂₃BrClF₃N₆(1337567-05-1)

Safety Data

• Hazardous Substances Data: 1337567-05-1(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 114152-23-7 2-(2,3,6-trifluorophenyl)acetic acid 
• 27007-53-0 methyl-2-bromo-5-chlorobenzoate 
• 1228788-17-7 1-(2-bromo-5-chlorophenyl)-2-(2,3,6-trifluorophenyl)ethanone 
• 709639-84-9 benzyl-(6-chloro-2-methylsulfanylpyrimidin-4-yl)amine 
• 1337567-00-6 benzyl-(6-chloro-2-methanesulfonylpyrimidin-4-yl)amine 
• 1337567-01-7 C₁₁H₁₂ClN₅ 
• 1337567-02-8 C₂₅H₁₇BrCl₂F₃N₅ 
• 1337567-03-9 C₂₅H₁₆Cl₂F₃N₅ 
• 1337567-04-0 C₃₂H₂₄ClF₃N₆ 

Downstream Products

• 1337567-06-2 C₃₆H₂₈ClF₃N₈ 
• 1337565-36-2 2-[5-chloro-3-(2,3,6-trifluorobenzyl)-1H-indazol-1-yl]-5-(1-methyl-1H-pyrazol-4-yl)pyrimidine-4,6-diamine 

Relevant articles and documents

SOLUBLE GUANYLATE CYCLASE ACTIVATORS

The invention relates to compounds having the structure of Formula (I) and pharmaceutically acceptable salts thereof, which are soluble guanylate cyclase activators. The compounds are capable of modulating the body's production of cyclic guanosine monophosphate ("cGMP") and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The compounds are useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, pulmonary hypertension, angina pectoris, thromboses, restenosis, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver.