1337862-76-6

Basic information

• Product Name: (4R,5S)-1-benzyl-4-(tert-butyldimethylsilyloxy)-5-methylpyrrolidin-2-one
• Synonyms: (4R,5S)-1-benzyl-4-(tert-butyldimethylsilyloxy)-5-methylpyrrolidin-2-one
• CAS NO: 1337862-76-6
• Molecular Weight: 319.519
• Mol File: 1337862-76-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4R,5S)-1-benzyl-4-(tert-butyldimethylsilyloxy)-5-methylpyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S)-1-benzyl-4-(tert-butyldimethylsilyloxy)-5-methylpyrrolidin-2-one(1337862-76-6)
• EPA Substance Registry System: (4R,5S)-1-benzyl-4-(tert-butyldimethylsilyloxy)-5-methylpyrrolidin-2-one(1337862-76-6)

Safety Data

• Hazardous Substances Data: 1337862-76-6(Hazardous Substances Data)

Upstream product

• 324752-71-8 tert-butyl (1S,2R)-2-hydroxy-1-methylpent-4-enylcarbamate 
• 1337862-62-0 tert-butyl (2S,3R)-3-(tert-butyldimethylsilyloxy)hex-5-en-2-ylcarbamate 
• 1337862-69-7 (2S,3R)-tert-butyl 3-(tert-butyldimethylsilyloxy)-2-methyl-5-oxopyrrolidine-1-carboxylate 

Downstream Products

• 202743-07-5 (2S,3R)-1-benzyl-2-methylpyrrolidin-3-ol 
• 1337862-77-7 (2S,3S)-3-azido-1-benzyl-2-methylpyrrolidine 
• 202743-06-4 (4R,5S)-1-benzyl-4-(hydroxy)-5-methylpyrrolidin-2-one 
• 1352347-71-7 C₁₃H₁₉NO₃S 
• 202742-87-8 (2S,3S)-1-benzyl-2-methylpyrrolidin-3-amine 
• 75272-39-8 N-((2S,3S)-1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-(methylamino)benzamide 

Relevant articles and documents

A facile approach to trans-4,5-pyrrolidine lactam and application in the synthesis of nemonapride and streptopyrrolidine

An efficient approach to trans-4-hydroxylpyrrolidine lactams 1 starting from amino acid is described. The utility of this method has been demonstrated in the synthesis of antipsychotic nemonapride 3 and antiangiogenic streptopyrrolidine 4. Compared four s