1337862-77-7

Upstream product

• 50403-13-9 (3R,4R)-3,4-epoxypentan-1-ol 
• 764-37-4 (E)-3-penten-1-ol 
• 324752-71-8 tert-butyl (1S,2R)-2-hydroxy-1-methylpent-4-enylcarbamate 
• 1352347-71-7 C₁₃H₁₉NO₃S 
• 202743-06-4 (4R,5S)-1-benzyl-4-(hydroxy)-5-methylpyrrolidin-2-one 
• 1337862-62-0 tert-butyl (2S,3R)-3-(tert-butyldimethylsilyloxy)hex-5-en-2-ylcarbamate 
• 202743-07-5 (2S,3R)-1-benzyl-2-methylpyrrolidin-3-ol 
• 1337862-76-6 (4R,5S)-1-benzyl-4-(tert-butyldimethylsilyloxy)-5-methylpyrrolidin-2-one 
• 1337862-69-7 (2S,3R)-tert-butyl 3-(tert-butyldimethylsilyloxy)-2-methyl-5-oxopyrrolidine-1-carboxylate 

Downstream Products

• 202742-87-8 (2S,3S)-1-benzyl-2-methylpyrrolidin-3-amine 
• 75272-39-8 N-((2S,3S)-1-benzyl-2-methylpyrrolidin-3-yl)-5-chloro-2-methoxy-4-(methylamino)benzamide 

Relevant academic research and scientific papers

Concise, protecting-group-free synthesis of (+)-nemonapride via Eu(OTf)3-catalyzed aminolysis of 3,4-epoxy alcohol

A concise, protecting-group-free synthesis of the antipsychotic agent (+)-nemonapride has been achieved featuring a europium(III) trifluoromethanesulfonate (Eu(OTf)3)-catalyzed C4 selective aminolysis of a 3,4-epoxy alcohol by benzylamine and a

A facile approach to trans-4,5-pyrrolidine lactam and application in the synthesis of nemonapride and streptopyrrolidine

An efficient approach to trans-4-hydroxylpyrrolidine lactams 1 starting from amino acid is described. The utility of this method has been demonstrated in the synthesis of antipsychotic nemonapride 3 and antiangiogenic streptopyrrolidine 4. Compared four s