1337990-02-9Relevant articles and documents
Total synthesis and stereochemical revision of acortatarins A and B
Sudhakar, Gangarajula,Kadam, Vilas D.,Bayya, Shruthi,Pranitha, Gavinolla,Jagadeesh, Bharatam
, p. 5452 - 5455 (2011/12/05)
A first total synthesis of acortatarins A, B, and an enantiomer of the proposed structure of acortatarin B is described by using readily available d-sugars. This convergent total synthesis revealed the revision of the absolute configuration of acortatarin A and structural revision of acortatarin B. The key steps involved are regioselective epoxide opening with deprotonated 2,5-disubstituted pyrrole and spiroketalization.