13380-11-5

Upstream product

• 124-68-5 2-Amino-2-methyl-1-propanol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 736948-53-1 N-[2-(tert-butyl-dimethyl-silanyloxy)-1,1-dimethyl-ethyl]-4-methyl-benzenesulfonamide 
• 627079-75-8 N-allyl-4-methyl-N-(1,1-dimethylbuta-2,3-dienyl)phenylsulfonamide 
• 736947-55-0 N-allyl-N-(1-hydroxy-2-methylpropan-2-yl)-4-methylbenzenesulfonamide 
• 736947-58-3 N-allyl-N-(2-hydroxy-1,1-dimethylbut-3-ynyl)-4-methylphenylsulfonamide 
• 736948-57-5 methanesulfonic acid 1-{1-[allyl-(toluene-4-sulfonyl)-amino]-1-methyl-ethyl}-prop-2-ynyl ester 
• 736948-55-3 N-allyl-N-[2-(tert-butyl-dimethyl-silanyloxy)-1,1-dimethyl-ethyl]-4-methyl-benzenesulfonamide 
• 1041173-23-2 3,3-dimethyl-4-[(4-methylphenyl)sulfonyl]morpholine 
• 1109217-89-1 N-(1-hydroxy-2-methylprop-2-yl)-N-(prop-2-ynyl)-4-methylbenzenesulfonamide 
• 1226575-30-9 1-(1,1,1-trifluoroprop-2-en-2-yloxy)-2-methyl-N-tosylpropan-2-amine 

Relevant academic research and scientific papers

An annulation reaction for the synthesis of morpholines, thiomorpholines, and piperazines from β-heteroatom amino compounds and vinyl sulfonium salts

(Chemical Equation Presented) Heterocycling: Diphenyl vinyl sulfonium salt 1 acts first as an electrophile, then a base, and then again as an electrophile in this operationally simple, high yielding, one-pot synthesis of pharmacologically important morpholines, thiomorpholines, and piperazines. Compound 1 is an excellent synthon for the 1,2-ethane dication.

Enantio- and Regioselective Palladium(II)-Catalyzed Dioxygenation of (Aza-)Alkenols

An oxidative Pd-catalyzed intra-intermolecular dioxygenation of (aza-)alkenols has been reported, with total regioselectivity. To study the stereoselectivity, different chiral ligands as well as different hypervalent-iodine compounds have been compared. I

Pd(ii)-Catalyzed aerobic 1,2-difunctionalization of conjugated dienes: Efficient synthesis of morpholines and 2-morpholones

A novel and efficient methodology concerning the Pd(ii)-catalyzed intermolecular difunctionalization of conjugated dienes is reported to synthesize a series of functionalized morpholines and 2-morpholones. Widely distributed and easily obtained β-amino alcohols and α-amino acids, as starting nitrogen and oxygen sources, are successfully applied in the difunctionalization of conjugated dienes respectively. The majority of the desired products were obtained in moderate to excellent yields. Oxygen was successfully employed as a terminal oxidant. Further transformation of the generated products allowed for the expansion of structural diversity.

Gold-catalyzed direct activation of allylic alcohols in the stereoselective synthesis of functionalized 2-vinyl-morpholines

Alcohol versus alcohol: A highly stereocontrolled synthesis of substituted morpholines is realized by means of gold-catalyzed dehydrative allylic cyclization of diols (see scheme for one example; segphos = 5,5′-bis[di(3, 5-di-tert-butyl-4-methyoxyphenyl)phosphine]-4,4′-bi-1,3-benzodioxole). The present methodology represents one of the few examples of enantioselective gold-catalyzed transformations involving unactivated alkenes. Copyright

Palladium(0)-catalyzed stereoselective cyclization of allenenes: Divergent synthesis of pyrrolidines and 3-azabicyclo[3.1.0]hexanes from single allenenes

Two novel palladium(0)-catalyzed cyclizations of allenenes are described. Treatment of allenenes such as N-(1-alkyl-2,3-butadienyl)-N-allylsulfonamide with an aryl halide and K2CO3 in the presence of a catalytic amount of Pd(PPh

Synthesis and reaction of some 2-alkylene-1,3-oxazolidines

Starting from 1,3-oxazoline 6 synthesis of ketene-O,N-acetals 2b, 2c is described via NBS bromination and HBr elimination. The N-sulfonyl-oxazolidines 10, 11 are synthesized by cyclization starting from aminoalcoho17, 10d react with potassium t-butoxide t