Cas 1338052-47-3,5-fluoro-2'-deoxyuridine-5'-O-[1-naphthyl(benzoxy-L-phenylalaninyl)]phosphate

1338052-47-3

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Basic information

Product Name: 5-fluoro-2'-deoxyuridine-5'-O-[1-naphthyl(benzoxy-L-phenylalaninyl)]phosphate
Synonyms:
CAS NO:1338052-47-3
Molecular Formula:
Molecular Weight: 689.634
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 5-fluoro-2'-deoxyuridine-5'-O-[1-naphthyl(benzoxy-L-phenylalaninyl)]phosphate(CAS DataBase Reference)
NIST Chemistry Reference: 5-fluoro-2'-deoxyuridine-5'-O-[1-naphthyl(benzoxy-L-phenylalaninyl)]phosphate(1338052-47-3)
EPA Substance Registry System: 5-fluoro-2'-deoxyuridine-5'-O-[1-naphthyl(benzoxy-L-phenylalaninyl)]phosphate(1338052-47-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1338052-47-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1338052-47-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,8,0,5 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1338052-47:
(9*1)+(8*3)+(7*3)+(6*8)+(5*0)+(4*5)+(3*2)+(2*4)+(1*7)=143
143 % 10 = 3
So 1338052-47-3 is a valid CAS Registry Number.

1338052-47-3Upstream product

1338052-47-3Downstream Products

1338052-47-3Relevant academic research and scientific papers

PHOSPHORAMIDATE DERIVATIVES OF 5 - FLUORO - 2` - DEOXYURIDINE FOR USE IN THE TREATMENT OF CANCER

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Paragraph 0196-0200, (2014/03/24)

Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine are disclosed for use in the treatment of cancer, especially in the treatment of cancer where the patient shows resistance, for example, in a patient with cells with a lowered level of nucleoside tra

PHOSPHORAMIDATE DERIVATIVES OF 5 - FLUORO - 2 ' - DEOXYURIDINE FOR USE IN THE TREATMENT OF CANCER

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Page/Page column 53-54, (2012/09/21)

Phosphoramidate derivatives of 5-fluoro-2'-deoxyuridine are disclosed for use in the treatment of cancer, especially in the treatment of cancer where the patient shows resistance, for example, in a patient with cells with a lowered level of nucleoside transporter proteins and/or with nucleoside kinase-deficient cells and/or with mycoplasma-infected cells and/or with cells with a raised level of thymidylate synthase.

Phosphoramidate protides of the anticancer agent fudr successfully deliver the preformed bioactive monophosphate in cells and confer advantage over the parent nucleoside

McGuigan, Christopher,Murziani, Paola,Slusarczyk, Magdalena,Gonczy, Blanka,Vande Voorde, Johan,Liekens, Sandra,Balzarini, Jan

supporting information; experimental part, p. 7247 - 7258 (2011/12/21)

The fluorinated pyrimidine family of nucleosides continues to represent major current chemotherapeutic agents for treating solid tumors. We herein report their phosphate prodrugs, ProTides, as promising new derivatives, which partially bypass the dependen

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