1338075-44-7

Basic information

• Product Name: (2-(allyloxy)-4-fluorophenyl)methanol
• Synonyms: (2-(allyloxy)-4-fluorophenyl)methanol
• CAS NO: 1338075-44-7
• Molecular Weight: 182.195
• Mol File: 1338075-44-7.mol

Chemical Properties

• CAS DataBase Reference: (2-(allyloxy)-4-fluorophenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-(allyloxy)-4-fluorophenyl)methanol(1338075-44-7)
• EPA Substance Registry System: (2-(allyloxy)-4-fluorophenyl)methanol(1338075-44-7)

Safety Data

• Hazardous Substances Data: 1338075-44-7(Hazardous Substances Data)

Upstream product

• 345-29-9 4-fluorosalicylic acid 
• 1338075-42-5 methyl 2-(allyloxy)-4-fluorobenzoate 
• 392-04-1 methyl 4-fluoro-2-hydroxybenzoate 

Downstream Products

• 1207288-81-0 2-(allyloxy)-4-fluorobenzaldehyde 

Relevant articles and documents

The Synthesis of 5-Amino-dihydrobenzo[b]oxepines and 5-Amino-dihydrobenzo[b]azepines via Ichikawa Rearrangement and Ring-Closing Metathesis

The combination of Ichikawa's rearrangement and a ring-closing metathesis reaction of allyl carbamates is presented as a method for the preparation of 5-amino-substituted 2,5-dihydro-benzo[b]oxepines, 2,5-dihydro-benzo[b]azepines, and 2,5-dihydro-benzo[b]thiepins. It was demonstrated that the use of nonracemic allyl carbamates enables the synthesis of enantioenriched benzo-fused seven-membered heterocycles. Finally, it was shown that further functionalization of the obtained structures allows access to pharmacologically active 5-amino-substituted 2,3,4,5-tetrahydro-1-benzo[b]oxepine scaffolds.

MACROCYCLIC INTEGRASE INHIBITORS

Compound having Formula (I) and pharmaceutically acceptable salts or solvates thereof, their pharmaceutical formulations and use as HIV inhibitors.