1338326-93-4

Upstream product

• 120077-68-1 (4-bromo-3-chlorophenyl)methanol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1338326-92-3 (4-bromo-3-chlorobenzyl)(methyl)sulfane 
• 1338327-08-4 (S)-1-(4-bromo-3-chlorobenzyl)-3-(tert-butyldimethylsilyloxy)pyrrolidin-2-one 
• 1338326-91-2 1-bromo-2-chloro-4-(methylsulfonylmethyl)benzene 
• 1338327-07-3 (S)-3-(tert-butyldimethylsilyloxy)-1-(3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyrrolidin-2-one 
• 1338327-22-2 1-(3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)pyrimidin-2(1H)-one 
• 1338327-32-4 2-(2-chloro-4-(methylthiomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1338326-42-3 4-amino-6-(2'-chloro-4'-(methylsulfonylmethyl)biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one 
• 1338326-90-1 2-(2-chloro-4-(methylsulfonylmethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1338326-60-5 (S)-4-amino-6-(2'-chloro-4'-((3-hydroxy-2-oxopyrrolidin-1-yl)methyl)biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one 
• 1338327-06-2 (S)-4-amino-6-(4'-((3-(tert-butyldimethylsilyloxy)-2-oxopyrrolidin-1-yl)methyl)-2'-chlorobiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one 
• 1338326-70-7 (R)-4-amino-6-(2'-chloro-4'-(methylsulfonylmethyl)biphenyl-4-yl)-8-methyl-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one 
• 1338327-31-3 (R)-4-amino-6-(2'-chloro-4'-(methylthiomethyl)biphenyl-4-yl)-8-methyl-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one 
• 1338327-23-3 1-(4-bromo-3-chlorobenzyl)pyrimidin-2(1H)-one 

Relevant academic research and scientific papers

4 -AMINO -7,8- DIHYDROPYRIMIDO [5, 4 - F] [1, 4] OXAZEPIN- 5 ( 6H) - ONE BASED DGAT1 INHIBITORS

DGAT-1 inhibitor compounds of formula (I), pharmaceutically-acceptable salts and pro- drugs thereof are described, together with pharmaceutical compositions, processes for making them and their use in treating, for example, diabetes and obesity wherein, R1, R2, R3, R4, X2, q, Y1, Y2, n, Q and Z are as defined in the description.