1338360-54-5Relevant academic research and scientific papers
Syntheses of, and structural studies on, benzo-fused 1,2,4-thiadiazines
Clark, Ewan R.,Hayward, John J.,Leontowicz, Bryce J.,Eisler, Dana J.,Rawson, Jeremy M.
, p. 1755 - 1762 (2014)
The syntheses of nine benzo-fused-1,2,4-thiadizines are reported. The use of microwave synthesis has been shown to afford high yields and short reaction times in several key reaction steps. The molecular geometries of these heterocycles are discussed and
One-pot synthesis and asymmetric oxidation of 2-nitro-4-(trifluoromethyl) benzene containing sulfides
Rodygin, Konstantin S.,Rubtsova, Svetlana A.,Kutchin, Alexander V.,Slepukhin, Pavel A.
experimental part, p. 1885 - 1894 (2011/10/11)
An efficient one-pot method for the preparation of 2-nitro-4- (trifluoromethyl)benzene containing sulfides from 1,1'-disulfanediylbis[2-nitro- 4-(trifluoromethyl)benzene] is proposed. The corresponding enantiomerically enriched sulfoxides with up to 78% enantiomeric excess are prepared by the asymmetric oxidation of sulfides using a modified Sharpless method. The yield of sulfoxides is shown to decrease with an increase in the bulk of the aliphatic group and with a decrease of the inductive effect of the hydrocarbonic moiety on the sulfur atom. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Taylor & Francis Group, LLC.
