1338595-39-3

Upstream product

• 2751-27-1 4-iodobenzenesulfonyl hydrazide 
• 149512-01-6 1,2-dihydro-4-iodonaphthalene 
• 6345-64-8 1,2-bis(4-Iodophenyl)disulfane 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 624-38-4 para-diiodobenzene 
• 91-60-1 2-Naphthalenethiol 

Relevant academic research and scientific papers

By-Product-Catalyzed Redox-Neutral Sulfenylation/Deiodination/Aromatization of Cyclic Alkenyl Iodides with Sulfonyl Hydrazides

A by-product-catalyzed redox-neutral process has been established through tandem sulfenylation/deiodination/aromatization of cyclic alkenyl iodides with sulfonyl hydrazides. In the absence of external catalysts and additives a range of 4-iodo-1,2-dihydronaphthalenes reacted with sulfonyl hydrazides to give structurally diverse 2-naphthyl thioethers in good yields. Mechanistic studies showed that at an early stage sulfonyl hydrazides decomposed completely to thiosulfonates and disulfides and at a late stage the resulting thiosulfonates underwent tandem sulfenylation/deiodination/aromatization with 4-iodo-1,2-dihydronaphthalenes involving a [1,5]-sigmatropic hydrogen shift. Importantly, iodine was generated as a by-product from 4-iodo-1,2-dihydronaphthalenes upon heating and served as a catalyst for the decomposition of sulfonyl hydrazides and subsequent formation of 2-naphthyl thioethers. (Figure presented.).

Iodine-Promoted Tunable Synthesis of 2-Naphthyl Thioethers and 1-Naphthyl Thioethers

An iodine-promoted regioselective sulfenylation/deoxygenation/aromatization reaction of 1-tetralones with disulfides has been developed. This process could be modified to synthesize 2-naphthyl thioethers and 1-naphthyl thioethers in moderate to excellent

Diazaphospholane as an efficient ligand for copper-catalyzed cross-coupling of thiols with aryl iodides

Copper-catalyzed cross-coupling of thiols with aryl iodides performed well using an air-stable diazaphospholane ligand in presence of NaOH in DMF at 110 °C and a variety of diaryl sulfides are synthesized in good yields.