1338700-77-8Relevant articles and documents
Diastereoselective intramolecular friedel-crafts cyclizations of substituted methyl 2-(1 H-indole-1-carbonyl)acrylates: Efficient access to functionalized 1 H-pyrrolo[1,2-a]indoles
Patil, Dadasaheb V.,Cavitt, Marchello A.,France, Stefan
, p. 5820 - 5823 (2011/12/05)
A general, catalytic method for the diastereoselective synthesis of functionalized 1H-pyrrolo[1,2-a]indoles via an intramolecular Friedel-Crafts alkylation of N-acyl indoles is reported. Products were obtained in excellent yields (up to 98%) with high diastereoselectivities (up to >25:1 dr).