133871-96-2

Upstream product

• 64833-72-3 4,4-Dimethyl-2,3-dihydro-γ-pyran 
• 937-14-4 3-chloro-benzenecarboperoxoic acid 
• 22791-80-6 4,4-dimethyl-tetrahydro-pyran-2-one 
• 4160-82-1 3,3-dimethylglutaric anhydride 
• 72603-19-1 2-hydroxy-4,4-dimethyltetrahydropyran 

Downstream Products

• 133871-99-5 2-(Benzyloxy)-3-hydroxy-4,4-dimethyltetrahydropyran 
• 133871-94-0 2,3-Bis(benzyloxy)-4,4-dimethyltetrahydropyran 

Relevant academic research and scientific papers

Deuterium Isotope Effects in the Reaction of 4,4-Dimethyldihydropyran with Dimethyldioxirane

The reaction of dimethyldioxirane (1) with 4,4-dimethyl-2,3-dihydro-γ-pyran (2) gives the derived epoxide.Measured secondary deuterium isotope effects indicate that there is a greater degree of rehybridization at the β position (5-carbon) than at the α position (6-carbon) in the transition state leading to epoxide.The results are compared to those reported earlier in which 2 was oxidized by singlet oxygen to give the dioxetane.