1338715-22-2

Upstream product

• 1338719-05-3 C₂₉H₃₁FN₈O₃ 
• 1338718-76-5 C₂₃H₂₇BrN₈O₃ 
• 1338718-05-0 (R)-benzyl 1-(4-amino-1-methyl-1H-pyrazol-5-yl)azepan-4-ylcarbamate 
• 486424-37-7 3-amino-6-bromo-pyrazine-2-carboxylic acid 

Relevant academic research and scientific papers

PYRAZOL-4-YL-HETEROCYCLYL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE

Pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein X is a thiazolyl, picolinyl, pyridinyl, or pyrimidinyl, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.