1338727-49-3Relevant academic research and scientific papers
Synthesis and biological evaluation of new opioid agonist and neurokinin-1 antagonist bivalent ligands
Vardanyan, Ruben,Kumirov, Vlad K.,Nichol, Gary S.,Davis, Peg,Liktor-Busa, Erika,Rankin, David,Varga, Eva,Vanderah, Todd,Porreca, Frank,Lai, Josephine,Hruby, Victor J.
, p. 6135 - 6142 (2011)
Newly designed bivalent ligands - opioid agonist/NK1-antagonists have been synthesized. The synthesis of new starting materials - carboxy-derivatives of Fentanyl (1a-1c) was developed. These products have been transformed to 'isoimidium perchlorates' (2a-
