1338797-91-3Relevant academic research and scientific papers
Palladium-catalyzed reaction of 2-alkynylhalobenzene with 2-alkynylbenzamide: An efficient approach to indeno[1,2-c]azepin-3(2H)-ones
Luo, Yong,Wu, Jie
supporting information; experimental part, p. 11137 - 11139 (2011/11/06)
A novel and efficient route for rapid access to indeno[1,2-c]azepin-3(2H)- ones is described, which proceeds through a palladium-catalyzed tandem reaction of 2-alkynylhalobenzene with 2-alkynylbenzamide in the presence of PPh 3 or PCy3. The indeno[1,2-c]azepin-3(2H)-ones which incorporate both indene and unsaturated seven-membered ring lactam skeletons are obtained in good to excellent yields.
