1338813-99-2

Upstream product

• 114772-54-2 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile 
• 120568-11-8 2-(tetrazol-5-yl)-4'-methyl-1,1'-biphenyl 
• 124750-51-2 N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole 
• 114772-53-1 2-Cyano-4'-methylbiphenyl 
• 1338814-00-8 5-[4'-{(2,4-dioxo-1,3-thiazolidin-3-yl)methyl}-(1,1'-biphenyl)-2-yl]-1-trityl-1H-tetrazole 
• 1338813-97-0 4'-[(2,4-dioxo-1,3-thiazolidin-3-yl)methyl]-(1,1'-biphenyl)-2-carbonitrile 

Downstream Products

• 1338814-04-2 3-[{2'-(5-methyl-1,3,4-oxadiazol-2-yl)-(1,1'-biphenyl)-4-yl}methyl]-2,4-dioxo-1,3-thiazolidine 

Relevant academic research and scientific papers

Synthesis of biphenyl derivatives as ACE and α-amylase inhibitors

Angiotensin converting enzyme (ACE) and α-amylase inhibitors were synthesized using 4′-(bromomethyl)-biphenyl-2-carbonitrile 1 and various cyclic secondary amines (a-h). The nitrile group appended to biphenyl was converted into tetrazole 3a-3h and the tet

An efficient synthesis, X-ray and spectral characterization of biphenyl derivatives

Derivatives of 1,3-thiazolidin-2,4-dione appended to biphenyl ring viz., 7-9, 16-18 were prepared. The newly synthesized compounds were confirmed by IR, NMR (1H and 13(C) MS and elemental analyses. Single crystal X-ray diffraction study was carried out for one of the final compounds 9. Indian Academy of Sciences.