133891-58-4

Upstream product

• 133891-59-5 3-(aminoethyl)-1-(diphenylmethyl)-3-methylazetidine 
• 407-25-0 trifluoroacetic anhydride 
• 133891-88-0 1-benzhydryl-3-methylazetidine-3-carbonitrile 
• 133891-87-9 methanesulfonic acid 1-benzhydryl-3-methylazetidin-3-yl ester 

Downstream Products

• 756444-40-3 C₇H₁₁F₃N₂O 

Relevant academic research and scientific papers

The synthesis and biological evaluation of novel series of nitrile-containing fluoroquinolones as antibacterial agents

Several novel series of nitrile-containing fluoroquinolones with weakly basic amines are reported which have reduced potential for hERG (human ether-a-go-go gene) channel inhibition as measured by the dofetilide assay. The new fluoroquinolones are potent

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula (I) wherein A is formula (II), formula (III) or formula (IV), and B is formula (V), formula (VI), or formula (VII), can be used in a variety of applications including use as antibacterial agents.

7-Azetidinylquinolones as antibacterial agents. Synthesis and structure- activity relationships

A series of novel antibacterial quinolones and naphthyridones has been prepared which contain 7-azetidinyl substituents in place of the usual piperazine or aminopyrrolidine groups. These azetidinyl derivatives were evaluated for in vitro activity by deter

Substituted 1-diphenylmethyl azetidines

New azetidines, characterized in that they correspond to the general formula (I) STR1 in which R3 represents an amino radical, an alkylamino radical, a dialkylamino radical, a cycloalkylamino radical, an acylamino radical, an alkylacylamino radical, an aminomethyl radical, an alkylaminomethyl radical, an acylaminomethyl radical or an alkylacylaminomethyl radical, in which radicals each acyl fragment may be substituted with one or more halogen, especially fluorine, atoms; and R1, R2, R4, R5 and R6 represent a hydrogen atom or a lower alkyl radical, with the proviso that at least one of them represents a lower alkyl radical, and also their salts.