133901-12-9Relevant academic research and scientific papers
SYNTHESIS OF SOME NEW N,N,N'-DICYCLOHEXYLUREAS AND 4-THIAZOLIDINONES AND &β-LACTAMS THEREFROM
El-Ezbawy, S. R.,Abdel-Wahab, A. A.
, p. 127 - 133 (2007/10/02)
4-Thiazolidinones (10) and β-lactams (12) of anticipated biological activities were prepared via reaction of N N,N'-dicyclohexylureas (8) with mercaptoacetic acid and chloroacetyl chloride, respectively.The title compound, N(4-aminobenzoyl)-N,N'-dicyclohexylurea (4), was obtained via interaction of 4-aminobenzoic acid (2) with dicyclohexylcarbodiimide (1).Condensation of (4) with aromatic aldehydes afforded the corresponding arylidene derivatives (8) in good yield.Biological screening of selected products was done against some strains of bacteria.
