133908-45-9Relevant academic research and scientific papers
Searching for New Polymorphs by Epitaxial Growth
Simbrunner, Josef,Schrode, Benedikt,Hofer, Sebastian,Domke, Jari,Fritz, Torsten,Forker, Roman,Resel, Roland
, p. 568 - 578 (2021)
The formation of unknown polymorphs due to the crystallization at a substrate surface is frequently observed. This phenomenon is much less studied for epitaxially grown molecular crystals since the unambiguous proof of a new polymorph is a challenging tas
Asymmetric Synthesis of γ-Lactones through Koga Amine-Controlled Addition of Enediolates to α,β-Unsaturated Sulfoxonium Salts
Peraino, Nicholas J.,Kaster, Sven H.,Wheeler, Kraig A.,Kerrigan, Nessan J.
, p. 606 - 615 (2017/04/26)
A chiral Koga amine-controlled asymmetric synthesis of cis-γ-lactones through a formal [3 + 2] cycloaddition of enediolates with α,β-unsaturated sulfoxonium salts is described. The desired structural motif was formed in moderate to good yields (50-71% for 13 examples), with good to very good diastereoselectivity (dr 5:1 to 10:1 for 20 examples), favoring the cis-isomer, and good to excellent enantioselectivity (70-91% ee for 13 examples).
