133922-58-4Relevant articles and documents
Synthesis of trifluoromethyl-promoted functional pyrazolo[1,5-a]pyrimidine and pyrazolo[5,1-d][1,2,3,5]tetrazine-4(3H)-ones
Wu, Yan-Chao,Chen, Yong-Jun,Li, Hui-Jing,Zou, Xiao-Mao,Hu, Fang-Zhong,Yang, Hua-Zheng
, p. 409 - 416 (2006)
Ethyl 5-amino-3-trifluoromethyl-1H-pyrazole-4-carboxylate (1) was efficiently synthesized via the condensation of ethyl cyanoacetate and trifluoroacetic anhydride, followed by chloridization and the condensation with aqueous hydrazine. Its unique reactivi