133978-15-1

Basic information

• Product Name: 2-OCTYL CYANOACRYLATE
• Synonyms: 2-OCTYL CYANOACRYLATE;Octan-2-yl 2-cyanoprop-2-enoate
• CAS NO: 133978-15-1
• Molecular Formula: C12H19NO2
• Molecular Weight: 209.28476
• Mol File: 133978-15-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 297.6±23.0 °C(Predicted)
• Appearance: /
• Density: 0.956±0.06 g/cm3(Predicted)
• Vapor Pressure: 3.7Pa at 20℃
• CAS DataBase Reference: 2-OCTYL CYANOACRYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-OCTYL CYANOACRYLATE(133978-15-1)
• EPA Substance Registry System: 2-OCTYL CYANOACRYLATE(133978-15-1)

Safety Data

• Hazardous Substances Data: 133978-15-1(Hazardous Substances Data)

Usage

Indications

2-Octyl cyanoacrylate (Dermabond) is a fast-setting topical skin adhesive intended to close easily approximated skin edges of wounds from surgical incisions, including punctures from minimally invasive surgery and simple, thoroughly cleansed, trauma-induced lacerations. It may be used in conjunction with, but not in place of, subcuticular sutures. It is contraindicated for use on any wounds with evidence of active infection, areas under high skin tension, mucocutaneous surfaces, or skin regularly exposed to body fluids. Patients with formaldehyde allergies may react to this topical solution.

Upstream product

• 628-51-3 diacetoxymethane 
• 52688-08-1 2-octyl cyanoacetate 
• 50-00-0 formaldehyd 

Relevant articles and documents

Method for preparing glue and medical glue

The present invention provides a method for preparing an acrylate based adhesive in high purity, which performs a process of producing an alkyl cyanoacrylate polymer from alkyl cyanoacetate and a process of depolymerizing the alkyl cyanoacrylate polymer into monomers together to reduce the production costs.(AA) Mix alkyl alcohol with an organic solvent(BB) Add cyanoacetic acid and strong acid to the mixed solution and heating the same for esterification(CC) Remove water produced during the esterification reaction by azeotropic distillation and purify/dry the mixture(DD) Stir alkyl cyanoacetate, a crosslinking agent, and a catalyst to prepare a polymer(EE) Prepare a crude polymer from the polymer(FF) Perform catalytic depolymerization of the crude polymer to obtain a monomer-type high purity polymerCOPYRIGHT KIPO 2018

RAPIDLY CURING CYANOACRYLATES AS ADHESIVES

The present invention relates to a polymerizable adhesive composition which comprises, at least as one constituent, a cyanacrylate component and which requires a comparitively short time for curing when used on surfaces. The present invention therefore also includes a method for the production of the cyanacrylate component described above, and the cyanacrylate component as such.

Method for producing a cyanoacrylate monomer

A method for producing a cyanoacrylate monomer, comprising the steps of (a) reacting cyanoacetate and formaldehyde or paraformaldehyde in the presence of a base or amine base catalyst to form an α-cyanoacrylate prepolymer or oligomer mixture; (b) subjecting the α-cyanoacrylate prepolymer or oligomer mixture to a substrate having free acid, acid derivative, or free aldehyde or ketone groups to remove the catalyst and to obtain a purified α-cyanoacrylate prepolymer or oligomer; and (c) subjecting the purified α-cyanoacrylate prepolymer or oligomer to depolymerization to obtain an α-cyanoacrylate monomer.