133985-27-0

Upstream product

• 394220-70-3 (1H-indol-3-yl)-acetic acid 1-(3-bromo-4-methoxy-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl ester 
• 394220-69-0 2-[(S)-2-(3-Bromo-4-methoxy-phenyl)-2-hydroxy-ethyl]-isoindole-1,3-dione 
• 395639-54-0 (S)-1-(3-Bromo-4-methoxy-phenyl)-ethane-1,2-diol 
• 395639-55-1 (S)-2-(3-Bromo-4-methoxy-phenyl)-oxirane 
• 34039-30-0 2-bromo-1-methoxy-4-vinylbenzene 
• 34841-06-0 3-bromo-4-methoxybenzylaldehyde 
• 394220-71-4 N-[2-(3-bromo-4-methoxy-phenyl)-2-hydroxy-ethyl]-2-(1H-indol-3-yl)-acetamide 

Downstream Products

• 133985-30-5 Chelonin B N,O-diacetate 

Relevant academic research and scientific papers

The asymmetric synthesis and stereochemical assignment of chelonin B

The first total synthesis of the marine natural product (S)-(+)-chelonin B is described. The key reactions employed include Sharpless asymmetric dihydroxylation of a styrene derivative, catalytic ring-opening of an epoxide and sequential deprotection-rearrangement of a phthalimido indole acetate.