394220-70-3

Basic information

• Product Name: (1H-indol-3-yl)-acetic acid 1-(3-bromo-4-methoxy-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl ester
• Synonyms: (1H-indol-3-yl)-acetic acid 1-(3-bromo-4-methoxy-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl ester
• CAS NO: 394220-70-3
• Molecular Weight: 533.378
• Mol File: 394220-70-3.mol

Chemical Properties

• CAS DataBase Reference: (1H-indol-3-yl)-acetic acid 1-(3-bromo-4-methoxy-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1H-indol-3-yl)-acetic acid 1-(3-bromo-4-methoxy-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl ester(394220-70-3)
• EPA Substance Registry System: (1H-indol-3-yl)-acetic acid 1-(3-bromo-4-methoxy-phenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl ester(394220-70-3)

Safety Data

• Hazardous Substances Data: 394220-70-3(Hazardous Substances Data)

Upstream product

• 395639-54-0 (S)-1-(3-Bromo-4-methoxy-phenyl)-ethane-1,2-diol 
• 395639-55-1 (S)-2-(3-Bromo-4-methoxy-phenyl)-oxirane 
• 34039-30-0 2-bromo-1-methoxy-4-vinylbenzene 
• 34841-06-0 3-bromo-4-methoxybenzylaldehyde 
• 87-51-4 indole-3-acetic acid 
• 394220-69-0 2-[(S)-2-(3-Bromo-4-methoxy-phenyl)-2-hydroxy-ethyl]-isoindole-1,3-dione 
• 136918-14-4 phthalimide 

Downstream Products

• 133985-27-0 (S)-(+)-chelonin B 
• 394220-71-4 N-[2-(3-bromo-4-methoxy-phenyl)-2-hydroxy-ethyl]-2-(1H-indol-3-yl)-acetamide 

Relevant articles and documents

The asymmetric synthesis and stereochemical assignment of chelonin B

The first total synthesis of the marine natural product (S)-(+)-chelonin B is described. The key reactions employed include Sharpless asymmetric dihydroxylation of a styrene derivative, catalytic ring-opening of an epoxide and sequential deprotection-rearrangement of a phthalimido indole acetate.