134004-79-8Relevant academic research and scientific papers
Cross-coupling of aromatic aldehydes with n-(Amidobenzyl)benzotriazoles: An alternative route to α-amidoketones
Waengdongbung, Wijitra,Nontakitticharoen, Mongkol,Hahnvajanawong, Viwat
, p. 838 - 844 (2018/11/06)
Background: Several transition-metal-catalyzed reactions have been used to synthesize biologically active α-amidoketones. These approaches involve inconvenient conditions or expensive catalysts. Alternative attempts based on transition-metal-free catalyst
N-(1-Benzotriazol-1-ylalkyl)amides, Versatile α-Amidoalkylation Reagents. 1. α-Amidoalkylation of CH Acids
Katritzky, Alan R.,Pernak, Juliusz,Fan, Wei-Qiang,Saczewski, Franciszek
, p. 4439 - 4443 (2007/10/02)
N-(1-Benzotriazol-1-ylalkyl)amides 2, easily prepared from an amide and an aldehyde with benzotriazole, react smoothly with CH acids under mild conditions to give the α-amidoalkylation products in good yields.Benzotriazole aminals also react with CH acids in the presence of methyl iodide.
