134004-81-2

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 122-78-1 phenylacetaldehyde 
• 55-21-0 benzamide 

Downstream Products

• 137570-65-1 N-(1-Ethoxy-2-phenyl-ethyl)-benzamide 
• 139059-28-2 bis<(1-benzamido-2-phenyl)ethyl> sulfide 
• 134004-90-3 2-(1-Benzoylamino-2-phenyl-ethyl)-2-ethyl-malonic acid diethyl ester 
• 92-71-7 2,5-diphenyloxazole 
• 5202-77-7 N-[(Z)-2-phenylethenyl]benzamide 
• 78007-47-3 trans-N-styryl-benzamide 
• 134004-89-0 2-(1-Benzoylamino-2-phenyl-ethyl)-2-methyl-malonic acid diethyl ester 
• 139059-35-1 N-(1-octylthio-2-phenylethyl)benzamide 
• 99355-57-4 N-(1-Methoxy-2-phenyl-ethyl)-benzamide 

Relevant academic research and scientific papers

A novel route to N-styrylamides

A general synthesis of N-styrylamides starting from amides and phenylacetaldehyde is described. Condensation of the amide, aldehyde and benzotriazole affords N-(1-benzotriazol-1-yl-2-phenylethyl)amides 2 from which the benzotriazole molecule is smoothly eliminated.

Iodine(III)-promoted synthesis of oxazoles through oxidative cyclization of N -styrylbenzamides

The hypervalent iodine reagent PhI(OTf)2, generated in situ, has been successfully utilized in an intramolecular oxidative cyclization of N-styrylbenzamides. In remarkably short reaction times, the desired 2,5-disubstituted oxazoles were isolated in high yields in this metal-free oxidative C-O bond-forming reaction. Georg Thieme Verlag Stuttgart, New York.

N-(1-Benzotriazol-1-ylalkyl)amides, Versatile α-Amidoalkylation Reagents. 1. α-Amidoalkylation of CH Acids

N-(1-Benzotriazol-1-ylalkyl)amides 2, easily prepared from an amide and an aldehyde with benzotriazole, react smoothly with CH acids under mild conditions to give the α-amidoalkylation products in good yields.Benzotriazole aminals also react with CH acids in the presence of methyl iodide.