134005-06-4

Upstream product

• 75-52-5 nitromethane 
• 120803-36-3 1-morpholino[(phenyl)methyl]benzotriazole 
• 95-14-7 1,2,3-Benzotriazole 
• 5153-67-3 nitrostyrene 
• 102-96-5 (2-nitroethenyl)benzene 
• 625-33-2 3-penten-2-one 

Relevant academic research and scientific papers

Enantioselective organocatalytic Michael addition reactions between N-heterocycles and nitroolefins

A method for Michael addition of N-heterocycles to nitroolefins has been developed. The process is promoted by a cinchona alkaloid derivative to give Michael adducts in moderate to high enantioselectivities.

Conjugate addition nitro-Mannich reaction of carbon and heteroatom nucleophiles to nitroalkenes

The conjugate addition nitro-Mannich reactions of ethyl-β-nitroacrylate (1) and β-nitrostyrene (2) with electron rich aromatic nucleophiles, stabilized carbanions, alcohols, amines, thiols, and diphenyl phosphine oxide were investigated. The one pot conju

Uncatalysed intermolecular aza-Michael reactions

The catalyst-free reactions of activated alkenes with primary and secondary amines were investigated leading to various mono- and di-hydroamination products, the latter being rare and original. These reactions were shown to depend first on the strength of the nucleophile. Temperature and steric hindrance of the reagents were the other key factors controlling the selectivity of these aza-Michael reactions. In spite of their poor nucleophilicities, some N-heterocyclic amines could react with different activated alkenes affording valuable intermediates. Such results tended to demonstrate the hydrogen-bonding interactions between activated alkenes and poly-nitrogen aromatic cycles may control these concerted or fully conjugate aza-Michael additions.

Acidic-functionalized ionic liquid as an efficient, green and reusable catalyst for hetero-Michael addition of nitrogen, sulfur and oxygen nucleophiles to α,β-unsaturated ketones

A series of acidic-functionalized ionic liquids were synthesized and applied to the hetero-Michael addition of nitrogen, sulfur and oxygen nucleophiles to α,β-unsaturated ketones under solvent-free conditions. Notably, 1-methylimidazolium p-toluenesulfoni

A practical synthesis of 1,2-nitroamines by Michael addition of N-nucleophiles to nitroalkenes

A practical method for the synthesis of-nitroamines by Michael addition of azide to nitroalkene has been developed. This reaction proceeds in high yields under very mild conditions (phase-transfer catalysis) and is found to be general; good yields are obtained with both aryl and alkyl derivatives as well as with 1,1-di-substituted ones. Georg Thieme Verlag Stuttgart - New York.

N-(1-Benzotriazol-1-ylalkyl)amides, Versatile α-Amidoalkylation Reagents. 1. α-Amidoalkylation of CH Acids

N-(1-Benzotriazol-1-ylalkyl)amides 2, easily prepared from an amide and an aldehyde with benzotriazole, react smoothly with CH acids under mild conditions to give the α-amidoalkylation products in good yields.Benzotriazole aminals also react with CH acids in the presence of methyl iodide.