134037-95-9

Upstream product

• 2018-66-8 Z-Leu-OH 

Downstream Products

• 10473-38-8 N-(benzyloxycarbonyl)-L-leucyl-L-phenylalanine methyl ester 
• 648936-16-7 (-)-(3aR,6aS)-[(1S)-1-((6S)-4-benzoyl-6-hydroxyhexahydropyrrolo[3,2-b]pyrrole-1-carbonyl)-3-methylbutyl]carbamic acid benzyl ester 
• 648936-11-2 (-)-(3aR,6aS)-[(1S)-1-(4-benzoyl-6,6-dimethoxyhexahydropyrrolo[3,2-b]pyrrole-1-carbonyl)-3-methylbutyl]carbamic acid benzyl ester 
• 51021-87-5 N-benzyloxycarbonyl-L-leucine methyl ester 
• 176217-51-9 (2R,3S)-3-((S)-2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-2-isopropyl-4-oxo-azetidine-1-carboxylic acid tert-butyl ester 
• 648936-13-4 (-)-(3aR,6aS)-N-[(1S)-1-(4-benzoyl-6,6-dimethoxyhexahydropyrrolo[3,2-b]pyrrole-1-carbonyl)-3-methylbutyl]-4-tert-butylbenzamide 
• 648936-18-9 (-)-(3aR,6aS)-N-[(1S)-1-((6S)-4-benzoyl-6-hydroxyhexahydropyrrolo[3,2-b]pyrrole-1-carbonyl)-3-methylbutyl]-4-tert-butylbenzamide 
• 648936-12-3 (2S,3aR,6aS)-2-amino-1-(4-benzoyl-6,6-dimethoxyhexahydropyrrolo[3,2-b]pyrrol-1-yl)-4-methylpentan-1-one 
• 648936-17-8 (2S,3aR,6aS)-2-amino-1-((6S)-4-benzoyl-6-hydroxyhexahydropyrrolo[3,2-b]pyrrol-1-yl)-4-methylpentan-1-one 
• 1027367-46-9 [(S)-1-((2R,3S)-2-Isopropyl-4-oxo-azetidin-3-ylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Amino acid fluorides: Their preparation and use in peptide synthesis

Z or Fmoc amino acid fluorides have been prepared from the protected amino acids and cyanuric fluoride, and have been tested both in the condensation with simple amino acid esters and in Solid Phase Peptide Synthesis.

Synthesis and evaluation of cis-hexahydropyrrolo[3,2-b]pyrrol-3-one peptidomimetic inhibitors of CAC1 cysteinyl proteinases

A stereoselective synthesis of functionalised cis-hexahydropyrrolo[3,2-b] pyrrol-3-ones has been developed through Fmoc and Cbz-protected intermediates 5 and 6. Building blocks 5 and 6 were prepared via the intramolecular cyclisation of anti-epoxide 17. T

BIOLOGICALLY ACTIVE COMPOUNDS

Compounds of general formula (I) wherein: Z = CR3R4, where R3 and R4 are independently chosen from CO-7-alkyl P1 = CR5R6, P2 = O, CR7R8/sup