1340372-11-3 Usage
Uses
Used in Pharmaceutical Research:
1-(Tetrahydro-pyran-4-yl)-1H-pyrazole-4-carboxylic acid is used as a chemical intermediate for the development of new pharmaceutical compounds due to its unique structure and functional groups that can be modified to create derivatives with diverse properties.
Used in Drug Development:
In the pharmaceutical industry, 1-(Tetrahydro-pyran-4-yl)-1H-pyrazole-4-carboxylic acid is utilized as a key component in the synthesis of potential drug candidates, leveraging its ability to participate in esterification and other chemical reactions to form bioactive molecules.
Used in Medicinal Chemistry:
1-(Tetrahydro-pyran-4-yl)-1H-pyrazole-4-carboxylic acid serves as a valuable chemical for further study in medicinal chemistry, where its structural complexity and potential biological activity can be explored for the design of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1340372-11-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,4,0,3,7 and 2 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1340372-11:
(9*1)+(8*3)+(7*4)+(6*0)+(5*3)+(4*7)+(3*2)+(2*1)+(1*1)=113
113 % 10 = 3
So 1340372-11-3 is a valid CAS Registry Number.
1340372-11-3Relevant academic research and scientific papers
METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION
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Paragraph 0662-0663, (2021/11/20)
Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer. The present disclosure describes compounds and methods to recover wild-type function to p53 mutants. The compounds of the present disclosure can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA and activate downstream effectors involved in tumor suppression. The disclosed compounds can be used to reduce the progression of cancers that contain a p53 mutation.
NEW POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTOR
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Page/Page column 53, (2014/04/17)
The present invention relates to indole derivatives useful in therapy, to compositions comprising said compounds, and to methods of treating diseases comprising administration of said com- pounds. The compounds referred to are positive allosteric modulators (PAMs) of the nicotinic acetylcholine α7 receptor.
