1340487-51-5

Basic information

• Product Name: 3-(3,4-difluorophenyl)-5-methylpyridin-2-amine
• Synonyms: 3-(3,4-difluorophenyl)-5-methylpyridin-2-amine
• CAS NO: 1340487-51-5
• Molecular Weight: 220.222
• Mol File: 1340487-51-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(3,4-difluorophenyl)-5-methylpyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-difluorophenyl)-5-methylpyridin-2-amine(1340487-51-5)
• EPA Substance Registry System: 3-(3,4-difluorophenyl)-5-methylpyridin-2-amine(1340487-51-5)

Safety Data

• Hazardous Substances Data: 1340487-51-5(Hazardous Substances Data)

Upstream product

• 17282-00-7 3-bromo-5-methylpyridin-2-amine 
• 168267-41-2 (3,4-difluorophenyl)boronic acid 

Downstream Products

• 1397286-94-0 ((rac)-3-exo-8-(2-chloropyridin-4-yl)-8-azabicyclo[3.2.1]octan-3-yl)-8-(3,4-difluorophenyl)-6-methyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine 
• 1397287-27-2 ((rac)-3-exo-8-benzyl-8-azabicyclo[3.2.1]octan-3-yl)-8-(3,4-difluorophenyl)-6-methyl-[1,2,4]triazolo[1,5-a]pyridin-2-amine 
• 1397287-26-1 methyl N'-((rac)-3-exo-8-benzyl-8-azabicyclo[3.2.1]octan-3-yl)-N-(3-(3,4-difluorophenyl)-5-methylpyridin-2-yl)carbamimidothioate 
• 1397287-25-0 1-((rac)-3-exo-8-benzyl-8-azabicyclo[3.2.1]octan-3-yl)-3-(3-(3,4-difluorophenyl)-5-methylpyridin-2-yl)thiourea 
• 1397287-24-9 3-(3,4-difluorophenyl)-2-isothiocyanato-5-methylpyridine 

Relevant articles and documents

BRIDGED PIPERIDINE DERIVATIVES

The present invention relates to compounds of formula I hetaryl I, hetaryl II, R1, R2, R3, Y, m, and o or to pharmaceutically active acid addition salts thereof. The present compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposition of β-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.