134053-28-4

Basic information

• Product Name: (3S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-[(S)-3-(tert-butyl-dimethyl-silanyloxy)-3-cyclohexyl-prop-1-ynyl]-2-methylene-cyclopentanone
• CAS NO: 134053-28-4
• Molecular Weight: 476.847
• Mol File: 134053-28-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-[(S)-3-(tert-butyl-dimethyl-silanyloxy)-3-cyclohexyl-prop-1-ynyl]-2-methylene-cyclopentanone(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-[(S)-3-(tert-butyl-dimethyl-silanyloxy)-3-cyclohexyl-prop-1-ynyl]-2-methylene-cyclopentanone(134053-28-4)
• EPA Substance Registry System: (3S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-3-[(S)-3-(tert-butyl-dimethyl-silanyloxy)-3-cyclohexyl-prop-1-ynyl]-2-methylene-cyclopentanone(134053-28-4)

Safety Data

• Hazardous Substances Data: 134053-28-4(Hazardous Substances Data)

Upstream product

• 134005-59-7 C₁₉H₃₇AlOSi 
• 117254-07-6 (4R)-2-(N,N-diethylamino)methyl-4-(t-butyldimethylsiloxy)-cyclopent-2-en-1-ol 

Relevant articles and documents

Highly Efficient Synthesis of 13-Dehydroprostaglandins by 1,4-Addition Reaction of Alkynyl ω Side-Chain Unit onto Cyclopentenone Framework

Optically active 2-((diethylamino)methyl)-4-siloxy-2-cyclopentenone (2) reacts with a diethyl(3-(tert-butyldimethylsiloxy)-1-alkynyl)aluminum compound via 1,4-addition pathway to afford the enone 5, useful intermediate for synthesis of PGs via two-component coupling process, in excellent yield, thus making it easy to synthesize 13-dehydro-PGs.