1340548-40-4Relevant academic research and scientific papers
Synthesis and antioxidant activities of Coenzyme Q analogues
Wang, Jin,Li, Shuo,Yang, Tao,Yang, Jian
, p. 710 - 713 (2014)
A series of 2,3-dimethoxy-5-methyl-1,4-benzoquinones (Coenzyme Q) substituted at the C-6 position with various groups were designed and synthesized based on the Coenzyme Q10 as potent antioxidant. In vitro antioxidant activities of these compounds were evaluated and compared with commercial antioxidant Coenzyme Q10 employing DPPH assay. All these synthesized Coenzyme Q analogues are found to exhibit good antioxidant activities. Of which Compound 8b bearing a N-benzoylpiperazine group at the C-6 position showed more potent inhibition of DPPH radical than Coenzyme Q10. All these results suggested the applicability of the Coenzyme Q analogues as potent antioxidants for combating oxidative stress.
A facile synthesis of 2, 3-dimethoxy-5-methyl-1, 4-benzoquinones
Wang, Jin,Yang, Jian,Zhou, Rong-Guang,Yang, Bo,Wu, Yuan-Shuang
, p. 428 - 430 (2011/10/08)
Several 2, 3-dimethoxy-5-methyl-1, 4-benzoquinones substituted at the C-6 position with alkoxy methyl groups were prepared by a reaction sequence starting from 2, 3, 4, 5-tetramethoxytoluene (alkoxy methyl) via a Blanc chloromethylation reaction, Williams
