1340585-67-2Relevant articles and documents
Asymmetric construction of trifluoromethylated pyrrolidines via Cu(i)-catalyzed 1,3-dipolar cycloaddition of azomethine ylides with 4,4,4-trifluorocrotonates
Li, Qing-Hua,Tong, Min-Chao,Li, Jun,Tao, Hai-Yan,Wang, Chun-Jiang
, p. 11110 - 11112 (2011)
Trifluoromethylated pyrrolidines have been synthesized via catalytic asymmetric 1,3-dipolar cycloaddition with excellent stereoselectivity for the first time. Epimerization of the endo-pyrrolidines obtained from cis-4,4,4-trifluorocrotonate into the exo-p