134070-91-0Relevant academic research and scientific papers
Lanthanoid-catalyzed ring-opening reaction of epoxides with acyl halides
Taniguchi, Yuki,Tanaka, Shintaro,Kitamura, Tsugio,Fujiwara, Yuzo
, p. 4559 - 4560 (1998)
Eu(dpm)3 [dpm: dipivaloylmethanate] catalyzes the ring-opening reaction of epoxides with acyl halides affording the corresponding 2-haloalkyl esters. The stereochemical course was confirmed as trans-addition in the case of the reaction of cyclo
Cobalt(II)chloride catalysed cleavage of ethers with acyl halides: Scope and mechanism
Iqbal,Srivastava
, p. 3155 - 3170 (2007/10/02)
Cobalt(II) chloride in acetonitrile catalyses the cleavage of a wide variety of ethers with acyl halides under mild conditions to give the corresponding esters in good yields. Acyclic aliphatic ethers are cleaved to the corresponding ester and chlorides whereas the cyclic aliphatic ethers give rise to the ω-chloroesters. The benzyl ethers can be converted to the corresponding esters along with the formation of benzyl chloride and benzyl acetamide. A comparative study for the cleavage of allyl and benzyl ether has revealed that benzyl ether can be selectively cleaved in presence of the allyl ethers. The oxiranes can be cleaved in highly regioselective manner to the corresponding-β-chloroesters. The vinyl ethers undergo sp2-hybridised carbon-oxygen bond cleavage under these conditions. Based on product analysis, a mechanism involving electron transfer followed by O-acylation and S(N)1 or S(N)2 attack by chloride-ion is discussed.
A General Method for the Separation of Enantiomeric trans-2-Substituted Cyclohexanols
Hoenig, Helmut,Seufer-Wasserthal, Peter
, p. 1137 - 1140 (2007/10/02)
An number of different racemic, trans-2-substituted cyclohexanols has been prepared in high optical purity by optical resolution of the respective 2'-substituted cyclohexyl butanoates with the aid of commercially available lipases.
