134074-38-7

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 105-45-3 acetoacetic acid methyl ester 
• 17356-08-0 thiourea 

Downstream Products

• 252756-58-4 5-(4-Methoxy-phenyl)-7-methyl-3-oxo-2-[1-phenyl-meth-(Z)-ylidene]-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid methyl ester 
• 324037-21-0 methyl 4-(4-methoxyphenyl)-6-methyl-2-(methylthio)-1,4-dihydropyrimidine-5-carboxylate 
• 1221719-89-6 7-acetyl-6-(4-methoxyphenyl)-8-methyl-2,3-dihydropyrimido[2,1-b][1,3]thiazin-4(6H)-one 
• 1375148-01-8 methyl 4-(4-methoxyphenyl)-6-methyl-2-phenyl-1,4-dihydropyrimidine-5-carboxylate 
• 144106-30-9 methyl-3-phenyl-5-(4-methoxyphenyl)-7-methyl-5H-thiazolo<3,2-a>pyrimidine-6-carboxylate 

Relevant academic research and scientific papers

Preyssler heteropolyacid supported on silica coated NiFe2O4 nanoparticles for the catalytic synthesis of bis(dihydropyrimidinone)benzene and 3,4-dihydropyrimidin-2(1H)-ones

A novel magnetic acidic catalyst comprising Preyssler (H14[NaP5W30O110]) heteropoly acid supported on silica coated nickel ferrite nanoparticles (NiFe2O4@SiO2) was prepared. The

Synthesis of dihydropyrimidinones: An improved conditions for the Biginelli reaction

A mild and selective method for the synthesis of dihydropyrimidinones using CBr4 in methanol in the Biginelli three component cyclocondensation reactions has been developed. Yields are significantly higher than utilizing classical Biginelli rea

In vitro and in silico biological studies of novel thiazolo[3,2-a] pyrimidine-6-carboxylate derivatives

In the present study, we report the synthesis, characterization of new series of thiazolo[3,2-a]pyrimidine-6-carboxylate derivatives 3a-f and 4a-f. The newly synthesized compounds were screened for in vitro antimicrobial and antiviral activities. The prob

Chitosan-silica sulfate nano hybrid: An efficient biopolymer based-heterogeneous nano catalyst for solvent-free synthesis of 3,4-dihydropyrimidine-2(1H)-one/thiones

A green and highly efficient approach for the synthesis of 3,4-dihydropyrimidine-2(1H)-one/thione derivatives is described. In this approach, the three-component Biginelli reaction between (thio)urea, methyl acetoacetate and aldehydes under solvent-free c

Vegetable oil as a highly effective 100% bio-based alternative solvent for the one-pot multicomponent Biginelli reaction

Multicomponent one-pot Biginelli reactions have been successfully performed using vegetable oil as bio-based, non-toxic, and environmentally friendly solvents. Palm oil was demonstrated to be a highly effective greener solvent as compared to petroleum-bas

Niobium Oxides as Heterogeneous Catalysts for Biginelli Multicomponent Reaction

This study reports a simple, reusable, and recoverable niobium-based heterogeneous catalysts for Biginelli multicomponent reactions. Different methods of catalysts preparation were investigated. For this purpose, HY-340 (Nb2O5·nH2O) and Nb2O5 were chemica

Br?nsted acidic 1-ethyl-1,2,4-trizolium phenylsulfonate as catalyst for biginelli reaction

A Br?nsted acidic 1-ethyl-1,2,4-triazolium phenylsulfonate has been synthesized and characterized. A catalytic study is performed for 1-ethyl-1,2,4-triazolium phenylsulfonate as acid catalyst for a multicomponent reaction of synthesis of series of 3,4-dih

Heteropoly acid supported on activated natural clay-catalyzed synthesis of 3,4-dihydropyrimidinones/thiones through Biginelli reaction under solvent-free conditions

Dihydropyrimidinones/thiones (DHPM’s) have been prepared by one-pot condensation of methyl acetoacetate, aldehydes, urea/thiourea in the presence of heteropoly-11-tungsto-1-vanadophosphoric acid, H4[PVW11O40] · 32H2/

Fe3O4@PEG-SO3H rod-like morphology along with the spherical nanoparticles: Novel green nanocomposite design, preparation, characterization and catalytic application

The design and preparation of polyethylene glycol sulfonic acid surface coated magnetic nanoparticles (Fe3O4@PEG-SO3H) is described. The morphology of the prepared nanocomposite was rod-like along with spherical nanopartic

Decoration of multi-walled carbon nanotubes with NiO nanoparticles and investigation on their catalytic activity to synthesize pyrimidinone heterocycles

A supported carbon material is shown to be a highly efficient, eco-friendly and recyclable solid acid catalyst for the Biginelli reaction of aldehyde, β-ketoester and urea or thiourea under microwave irradiation in the absence of solvent. This method offe