134122-77-3Relevant articles and documents
Synthesis and antifungal activity of d-glucopyranosyl ureas and d-glucofurano-imidazolidine-2-ones
Tang, Xuan,Xue, Feng,Ma, Hongju,Cao, Xiufang,Chen, Changshui,Li, Xuegang
, p. 805 - 820 (2013/06/05)
A series of N-β-d-glucopyranosyl-N'-substituted phenyl ureas were synthesized by reaction of glucosyl isocyanate with arylamines and glycosamine with aryl isocyanates, and a series of d-glucofurano-imidazolidine-2-ones were obtained via deacetylation of glycosylureas. Although some of the compounds have already been described, most were prepared for the first time in this work. The structures of all the compounds synthesized were confirmed by IR, 1H NMR, and, in part, by 13C NMR. Antifungal activity of the title compounds was determined against four kinds of plant pathogenic fungi, Sclerotinia sclerotiorum, Fusarium graminearum, Fusarium oxysporum, and Bipolaris maydis. Preliminary bioassay indicates that most of glycosylureas had some activity against S. sclerotiorum; for some, the antifungal activity was strong. However, most of the imidazolidine-2-ones had weak antifungal activity.
Reaction of 2-amino-2-deoxy-D-glucose with aryl and acyl isothiocyanates, and aryl isocyanates: structure of the intermediate products
Guzman, Jose Fernandez-Bolanos,Rodriguez, Salud Garcia,Fernandez-Bolanos, Jose,Dianez, Ma. Jesus,Lopez-Castro, Amparo
, p. 125 - 143 (2007/10/02)
The structure of (4R)-1-aryl-5-hydroxy-4-(D-arabino-tetritol-1-yl)imidazolidine-2-thiones (1-3), obtained by reaction of 2-amino-2-deoxy-D-glucose with aryl isothiocyanates, has been confirmed by 1H- and 13C-n.m.r. spectroscopy.Likewise, the structures of