4780-17-0Relevant articles and documents
Acetyl glucosamine imidazolemethanol -2, 4, 5-Trion synthetic method of use with bacteriostatic
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Paragraph 0030; 0032, (2017/02/23)
The invention discloses acetylglucosamine imidazol-2,4,5-trione, and further discloses a synthetic method of the acetylglucosamine imidazol-2,4,5-trione and antimicrobial application. The synthetic method is quick, efficient and high in productivity, and
Engineering Light-Mediated Bistable Azobenzene Switches Bearing Urea d -Aminoglucose Units for Chiral Discrimination of Carboxylates
D?browa, Kajetan,Niedba?a, Patryk,Jurczak, Janusz
, p. 3576 - 3584 (2016/05/24)
The symmetrical molecular receptors 1a and 1b consisting of a photochemically addressable azobenzene tether functionalized with urea hydrogen-bonding groups and d-carbohydrates as chiral selectors were developed to achieve control over the chiral recognition of α-amino acid-derived carboxylates. The photo- and thermally interconvertible planar E-1 and concaved Z-1 were found to exhibit different affinities, selectivities, and binding modes toward these biologically important anions in a highly polar medium (DMSO + 0.5% H2O). Binding affinity for the same enantiomerically pure guest was up to 3 times higher for E-1 than for Z-1 (cf. parameter β). In addition, the rate of thermal Z → E isomerization was found to depend on the chiral binding ability of Z-1, i.e., more strongly bound carboxylate enantiomer as well as higher enantiomer concentration caused faster relaxation to E-1.
Synthesis of novel glycosyl imidazolidine-2,4,5-trione derivatives
Liu, Wei Wei,Zhang, Qiang,Gong, Feng,Huo, Yun Feng,Tao, Chuan Zhou,Cao, Zhi Ling,Shi, Da Hua
, p. 161 - 165 (2015/03/05)
A series of glycosyl imidazolidine-2,4,5-trione derivatives were achieved by condensing per-O-acetylated glucosamine, triphosgene, amines and oxalyl chloride. The convenient and efficient method afforded the desired products with good to excellent yields
Synthesis and antifungal activity of d-glucopyranosyl ureas and d-glucofurano-imidazolidine-2-ones
Tang, Xuan,Xue, Feng,Ma, Hongju,Cao, Xiufang,Chen, Changshui,Li, Xuegang
, p. 805 - 820 (2013/06/05)
A series of N-β-d-glucopyranosyl-N'-substituted phenyl ureas were synthesized by reaction of glucosyl isocyanate with arylamines and glycosamine with aryl isocyanates, and a series of d-glucofurano-imidazolidine-2-ones were obtained via deacetylation of glycosylureas. Although some of the compounds have already been described, most were prepared for the first time in this work. The structures of all the compounds synthesized were confirmed by IR, 1H NMR, and, in part, by 13C NMR. Antifungal activity of the title compounds was determined against four kinds of plant pathogenic fungi, Sclerotinia sclerotiorum, Fusarium graminearum, Fusarium oxysporum, and Bipolaris maydis. Preliminary bioassay indicates that most of glycosylureas had some activity against S. sclerotiorum; for some, the antifungal activity was strong. However, most of the imidazolidine-2-ones had weak antifungal activity.
Synthesis of sugar isocyanates and their application to the formation of ureido-linked disaccharides
Avalos, Martin,Babiano, Reyes,Cintas, Pedro,Hursthouse, Michael B.,Jimenez, Jose L.,Light, Mark E.,Palacios, Juan C.,Perez, Esther M. S.
, p. 657 - 671 (2007/10/03)
The present work describes a facile and practical route to carbohydrate-based isocyanates, a reactive and appealing family of chiral heterocumulenes, wich can be easily converted into disaccharides and pseudodisaccharides interconnected by urea moieties.
New synthetic approaches to sugar ureas. Access to ureido-β- cyclodextrins
López, óscar,Maza, Susana,Maya, Inés,Fuentes, José,Fernández-Bola?os, José G.
, p. 9058 - 9069 (2007/10/03)
An efficient method for the preparation of urea-bridged cyclodextrins using triphosgene in the isocyanation step in an aqueous two-phase system is reported. Per-O-acetylated glycopyranosylamines and 2-amino-2-deoxy-α and β-d-glucose were also transformed
