134149-29-4Relevant academic research and scientific papers
Formation of Cyclohexanes in the Palladium Catalyzed Reaction of ε-Unsaturated Cyano Esters and Congeners
Bouyssi, D.,Coudanne, I.,Uriot, H.,Gore, J.,Balme, G.
, p. 8019 - 8022 (2007/10/02)
A previously described palladium-catalyzed cyclization leading to cyclopentane derivatives has been extended to the formation of cyclohexanes by disfavoring the competing Heck reaction.The nature of the nucleophile plays a prominent part in this generalization.
Palladium-mediated cyclopentanation of alkenes bearing a nucleophilic substituent. Stereochemistry and mechanism
Bouyssi, Didier,Balme, Genevieve,Fournet, Guy,Monteiro, Nuno,Gore, Jacques
, p. 1641 - 1644 (2007/10/02)
The increased facility of the reaction 11→2. 2 simultaneously with the increased nucleophilicity of the malonate, as well as the stereospecificity observed in the case of 3, led to the conclusion that the cyclisation proceeds by a nucleophilic attack on the double bond activated by a palladium(II) species.
