134150-03-1

Basic information

• Product Name: 4'-BROMO-4-(TRIFLUOROMETHOXY)BIPHENYL
• Synonyms: 4'-BROMO-4-(TRIFLUOROMETHOXY)BIPHENYL;4-BROMO-4'-TRIFLUOROMETHOXYDIPHENYL;4'-Bromo-4-(trifluoromethoxy)biphenyl 98%;4'-Bromo-4-(trifluoromethoxy)biphenyl98%
• CAS NO: 134150-03-1
• Molecular Formula: C13H8BrF3O
• Molecular Weight: 317.1
• Mol File: 134150-03-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 190.5 °C at 760 mmHg
• Flash Point: 62.8 °C
• Appearance: /
• Density: 1.37 g/cm³
• CAS DataBase Reference: 4'-BROMO-4-(TRIFLUOROMETHOXY)BIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-BROMO-4-(TRIFLUOROMETHOXY)BIPHENYL(134150-03-1)
• EPA Substance Registry System: 4'-BROMO-4-(TRIFLUOROMETHOXY)BIPHENYL(134150-03-1)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 134150-03-1(Hazardous Substances Data)

Usage

General Description

4'-Bromo-4-(trifluoromethoxy)biphenyl, also known as TBMB, is a chemical compound that consists of a biphenyl molecule with a bromine atom located at the 4' position and a trifluoromethoxy group at the 4-position. It is commonly used as a reagent in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. TBMB is a versatile building block with a wide range of applications, including as a precursor for the synthesis of biologically active compounds and as a ligand in metal-catalyzed reactions. It is known for its strong electron-withdrawing properties, making it useful for various chemical transformations. TBMB is considered to be a valuable tool in the field of organic chemistry due to its unique structural features and synthetic versatility.

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Relevant articles and documents

Photocatalyzed Transition-Metal-Free Oxidative Cross-Coupling Reactions of Tetraorganoborates**

Readily accessible tetraorganoborate salts undergo selective coupling reactions under blue light irradiation in the presence of catalytic amounts of transition-metal-free acridinium photocatalysts to furnish unsymmetrical biaryls, heterobiaryls and arylated olefins. This represents an interesting conceptual approach to forge C?C bonds between aryl, heteroaryl and alkenyl groups under smooth photochemical conditions. Computational studies were conducted to investigate the mechanism of the transformation.

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme glycolate oxidase (GO). Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

Liquid crystal compounds, liquid crystal medium and liquid crystal display

The instant invention relates to liquid crystal media comprising a strongly dielectrically positive component A, preferably comprising isothiocyanate compounds, most preferably compounds of formula I, as given in the text, and a further dielectrically positive component B, preferably comprising terminally polar substituted bi- or terphenyl compounds, most preferably comprising compounds of formula II, as given in the text, further to novel isothiocyanato compounds as well as to liquid crystal displays comprising these media, in particular to PDLC display and most particular to holographic PDLC displays. The instant invention further relates to compounds of formula I wherein the parameters are as as specified in the text.