71274-84-5 Usage
Uses
Used in Pharmaceutical Synthesis:
4-Trifluoromethoxy-biphenyl is used as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs with enhanced properties. The trifluoromethoxy group provides specific characteristics that can improve the efficacy and pharmacokinetics of the resulting compounds.
Used in Organic Chemistry:
In the realm of organic chemistry, 4-Trifluoromethoxy-biphenyl serves as a reagent in various chemical reactions. Its unique properties facilitate the preparation of biologically active molecules, making it an indispensable tool in the synthesis of complex organic compounds.
Used in Chemical Research and Development:
4-TRIFLUOROMETHOXY-BIPHENYL is also utilized in chemical research and development, where its trifluoromethoxy group imparts unique chemical properties that can be leveraged to explore new reaction pathways and create innovative chemical entities.
Used in the Synthesis of Organic Compounds:
4-Trifluoromethoxy-biphenyl is employed in the synthesis of a wide range of organic compounds, where its structural features can be manipulated to achieve desired outcomes in molecular design and synthesis processes.
Each of these applications underscores the versatility and importance of 4-Trifluoromethoxy-biphenyl in advancing the fields of chemistry and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 71274-84-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,2,7 and 4 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 71274-84:
(7*7)+(6*1)+(5*2)+(4*7)+(3*4)+(2*8)+(1*4)=125
125 % 10 = 5
So 71274-84-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H9F3O/c14-13(15,16)17-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H
71274-84-5Relevant academic research and scientific papers
Phenyl hydrazine as initiator for direct arene C-H arylation via base promoted homolytic aromatic substitution
Dewanji, Abhishek,Murarka, Sandip,Curran, Dennis P.,Studer, Armido
supporting information, p. 6102 - 6105 (2014/01/06)
A simple and efficient direct radical arylation of unactivated arenes is described which uses cheap and commercially available phenyl hydrazine as an initiator. The reaction occurs through a base promoted homolytic aromatic substitution (BHAS) mechanism involving aryl radicals and aryl radical anions as intermediates and offers a practical approach for preparation of an array of substituted biaryls.
Stille cross-coupling reactions with tin reagents supported on ionic liquids
Pham, Phuoc Dien,Vitz, Juergen,Chamignon, Cecile,Martel, Arnaud,Legoupy, Stephanie
experimental part, p. 3249 - 3257 (2009/12/24)
New ionic-liquid-supported tin reagents were synthesized and used in Stille cross-coupling reactions. High yields of biaryls were obtained under low-temperature, solvent-free, ligand-free conditions, with simple purification techniques. Moreover, the tin compound could be recycled up to five times without significant loss of reactivity. An expanded catalytic cycle for the Stille cross coupling reaction is proposed in order to explain side products that were formed under certain reaction conditions.
