134167-06-9Relevant academic research and scientific papers
MACROCYCLIC COMPOUNDS AS PROTEASOME INHIBITORS
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, (2019/05/02)
The compounds of the present invention are represented by the following compounds having Formula I and Formula (I'): where the substituents R1, R2, R2', R3, R4, R5, R', R", X, Y, and Z are as defined herein and where the substituents R1, R2, R3, R4, R5, R', R", X, Y, and Z are as defined herein. These compounds are used in the treatment of bacterial infections, parasite infections, fungal infections, cancer, immunologic disorders, autoimmune disorders, neurodegenerative diseases and disorders, inflammatory disorders, or muscular dystrophy or for providing immunosuppression for transplanted organs or tissues.
SYNTHESIS OF AN ETHYLENE GLYCOL CROSS-LINKED AMINO ACID
Ho, Mengfei,Wang, Weiheng,Douvlos, Maria,Pham, Thuha,Klock, Timothy
, p. 1283 - 1286 (2007/10/02)
Synthesis of an ethylene glycol-containing amino acid, (2R,9S)-N2-Cbz-N9-Boc-2,9-diamino-4,7-dioxadecanedioic acid 1-phenacyl 10-methyl diester 1, was studied through direct alkylation of N-Boc-L-serine and through BF3-catalyzed ring
