622-08-2 Usage
Description
Benzyl-PEG2-alcohol is a PEG linker with an acid labile, benzyl protecting group and a reactive primary alcohol. The primary alcohol can react and further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Chemical Properties
Ethylene glycol monobenzyl ether is a Colorless to light yellow liquid which will dissolve a large number of organic substances among which are oils, fats, greases, some vinyl resins, dewaxed damar, rosin, ester gum, etc. It is used principally as a high boiling solvent in lacquers, inks, and textile dyeing.
Uses
Different sources of media describe the Uses of 622-08-2 differently. You can refer to the following data:
1. 2-Benzyloxyethanol is used in a base-free iridium-catalyzed direct alkylation of active methylene compounds with alcohols.
2. 2-(Benzyloxy)ethanol has been used in:9-(2-hydroxyethyl)-linked synthesis of 2,6-diaminopurinessynthesis of benzyloxy ethyl methacrylate monomer by esterification with methacryloyl chloridea base-free iridium-catalyzed direct alkylation of active methylene compounds with alcohols
Synthesis Reference(s)
Tetrahedron Letters, 31, p. 389, 1990 DOI: 10.1016/S0040-4039(00)94562-3
Hazard
Toxic by ingestion.
Check Digit Verification of cas no
The CAS Registry Mumber 622-08-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 2 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 622-08:
(5*6)+(4*2)+(3*2)+(2*0)+(1*8)=52
52 % 10 = 2
So 622-08-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H12O2/c10-6-7-11-8-9-4-2-1-3-5-9/h1-5,10H,6-8H2
