134178-44-2Relevant academic research and scientific papers
RAS INHIBITORS
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Paragraph 0957; 0959, (2021/05/07)
The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers.
Diastereoselection in the conjugate additions of organocopper reagents to N-enoyloxazolidinones
Williams, David R.,Kissel, William S.,Li, Jie Jack
, p. 8593 - 8596 (2007/10/03)
A survey of conjugate additions of Yamamoto organocopper reagents to N- enoyl-4-substituted oxazolidinones is reported. Diastereofacial selectivity is reversed for 4-phenyl and 4-benzyloxazolidinones of the same relative configuration. Alkenylcopper reage
Lewis Acid Catalyzed Ene Reactions of α,β-Unsaturated N-Acyloxazolidinones
Snider, Barry B.,Zhang, Qingwei
, p. 4908 - 4913 (2007/10/02)
Chiral α,β-unsaturated N-acyloxazolidinones undergo a variety of Lewis acid catalyzed addition reactions to alkenes with modest to excellent asymmetric induction.The nature of the reaction is a function of alkene structure and reaction conditions.N-Croton
